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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. Which is the most effective method to improve the safety of the use of phytonadione in an institution with a 24-hour pharmacy?

A) Establishment of emergency preparedness kits containing phytonadione to be stored in the patient care areas where warfarin is used
B) Yearly in-service education and medical staff presentation about phytonadione use
C) Removal of phytonadione from all patient care areas of the facility coupled with strict usage guidelines
D) Computer order sets that default to using a standardized number of vials or amps of phytonadione per dose

2. A 24-year-old Woman complains of dysuria, hesitancy in urination, and frequent urination for the past 2 days. She has no costovertebral tenderness, fever, or history of UTls. Urinalysis data are:
* pH: 5.5
* WBCS: 15 cells/ul
* RBCS:5 Cells/uL
* Bacteria: Numerous Gram-negative rods
* Negative for protein, glucose, and WBC casts
For this patient, assuming that local resistance rates are low, which of the following would be an empiric cost-effective regimen?

A) Sulfamethoxazole/trimethoprim one double-strength tablet twice daily for 3 days
B) Amoxicillin 500 mg three times daily for 7 days
C) Azithromycin 1 g single dose
D) Ciprofloxacin 500mg twice daily for 7 days

3. When low molecular weight heparin is prescribed, in which of the following patient populations would monitoring anti-factor-Xa levels be reasonable to consider?

A) Anticardiolipin antibody syndrome
B) Protein C and Protein S deficiencies
C) Significant renal impairment
D) Past history of GI bleeding

4. A 47-year-old patient with type 2 diabetes mellitus and no known coronary heart disease has the following fasting lipid profile. HDL cholesterol = 40 mg/dL, LDL cholesterol = 164 mg/dL, and triglycerides = 150 mg/dL. The patient has an ASCVD 10-year risk score of 6%. According to the ACC/AHA, which of the following is the most appropriate intervention for this patient's LDL?

A) LDL lowering only warranted if the LDL was > 190 mg/dL
B) No indication to lower LDL
C) Reduce LDL by >50% (high intensity statin)
D) Reduce LDL by 30-50% (moderate intensity statin)

5. A 65-year-old woman on chronic hemodialysis presents with difficulty breathing and inability to sleep. The patient has had shortness of breath, diaphoresis, and nausea, but has not vomited.
She denies having abdominal pain, diarrhea, or chest pain. She has tachycardia and tachypnea, and exhibits peaked T waves with occasional PVCs on the ECG. Serum chemistry values are:
* Sodium: 137 mEq/L
* BUN: 125 mg/dL
* Potassium: 7.2 mEq/L
* Creatinine: 12.8 mg/dL
* Chloride: 97 mEq/L
* Glucose: 95 mg/dL
* HCO3- : 11 mEq/L
* Calcium: 8.5 mg/dL
* Albumin: 3.1 g/dL
* Phosphorus: 1.7 mg/dL
Which of the following should the pharmacotherapy specialist recommend for immediate therapy?

A) Sodium bicarbonate intravenously
B) Calcium gluconate intravenously
C) Sodium polystyrene sulfonate with sorbitol orally
D) Hemodialysis

Solutions: