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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A patient taking warfarin is seen in the clinic today and prescribed a 2-Week course of fluconazole for a fungal infection. Before the patient receives the first dose of fluconazole, the pharmacotherapy specialist should ensure that:

A) The fluconazole dose is administered at least 2 hours after the Warfarin dose.
B) The warfarin dose is empirically increased during fluconazole therapy.
C) An INR is obtained initially and monitored during fluconazole therapy.
D) The fluconazole prescription is changed to ketoconazole.

2. In a clinical trial, when would "intention to treat" analysis be most appropriate?

A) Crossover design
B) Small sample size
C) High drop-out rate
D) Phase || trial

3. A 50-year-old patient presents to the physician complaining of anxiety, insomnia, a depressed mood, and decreased energy level. Paroxetine therapy is initiated. Which symptom will be the last to respond?

A) Anxiety
B) Decreased energy
C) Insomnia
D) Depressed mood

4. A 72-year-old patient, weighing 72 kg and measuring 173 cm tall, presents to the emergency department with an acute ischemic stroke. The symptoms have been present for just over an hour. The patient has a history of hypertension and is currently taking lisinopril 10 mg daily.
The patient's evaluation reveals no intracerebral hemorrhaging. The current BP is 178/100 mm Hg. It is now 150 minutes from stroke symptom onset.
Which of the following should now be administered?

A) Intravenous glycoprotein IIb/IIIa inhibitor
B) An antihypertensive; reconsider intra-arterial thrombolytics once BP decreases
C) Intravenous-PA
D) An antihypertensive; reconsider intravenous t-PA once BP decreases

5. Initial efficacy data on an experimental drug in the United States are usually collected in:

A) Phase IV trials.
B) Phase trials.
C) Phase trials.
D) Phase III trials.

Solutions: