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ASCP MEDICAL LABORATORY TECHNICIAN - MLT(ASCP) Sample Questions:

1. The correct response is option B: The Hepatitis B "e" Antigen (HBeAg). This antigen indicates the virus is actively replicating and therefore the patient is very infectious. The hepatitis B "e" antigen is present when the virus is actively replicating. In cases of unintentional needlesticks, infectivity is of highest concern. The risk for infection is greatest during phases of increased HBeAg serology. The Hepatitis B surface antigen is the first detectable marker, but if the patient is known to have Hepatitis B already, it would be relatively unhelpful to confirm the condition with another HBsAG test. The core antigen is not detectable because it is covered by the nuclear envelope. Antibody response patterns would not be very helpful either as the patient has already been diagnosed with acute Hepatitis B. IgG antibodies would indicate recovery, which is not the case for this patient and IgM antibodies indicating a recent or acute infection would only confirm what is already known.
Recall, in cases of unintentional needlesticks, infectivity is of highest concern.
A phlebotomist at a local hospital recently had an accidental needle stick while drawing blood from a patient being treated for acute hepatitis B. Which serological marker from the patient would be of most value to the physician evaluating the phlebotomist's possible infection status?

A) Hepatitis B core Antigen (HBcAg)
B) Anti-Hepatitis B e (anti-HBe) IgM
C) Anti-Hepatitis B core (anti-HBc) IgG
D) Hepatitis B surface Antigen (HBsAg)
E) Hepatitis B e Antigen (HBeAg)

2. This antibody is found in the serum of Le(a-b-) secretors.
Which one of these Lewis blood group system phenotypes usually produces anti-Lea?

A) Le(a+b+)
B) Le(a--b-)
C) Le(a--b+)
D) Le(a+b-)

3. Donor and recipient blood samples (samples utilized for pre-transfusion compatibility testing) must be kept for at least 7 days after transfusion. Blood samples must be available to investigate a transfusion reaction, if necessary.
Donor and recipient blood samples must be kept for at least how long after transfusion?

A) 7 days
B) 10 days
C) Not a requirement
D) 3 days

4. The Fc portion of immunoglobulin can activate the classical complement pathway, where the heavy chains, light chains, hinge regions and Fab portions cannot.
Which part of the immunoglobulin molecule is responsible for activating complement?

A) heavy chains
B) light chains
C) Fc
D) Hinge regions
E) Fab

5. MCH is the average weight of hemoglobin in the average red blood cell. The value is expressed in picograms (10-12 grams).
Hematology
Hemoglobin (g/100ml) x 10 / RBC count (millions/mm3) is the formula for calculating:

A) MCV
B) MCHC
C) MCH
D) RDW

Solutions: